Consumption of red wine polyphenols reduces the susceptibility of low-density lipoproteins to oxidation in vivo
SV Nigdikar, NR Williams, BA Griffin… - The American Journal of …, 1998 - Elsevier
Red wine polyphenols (RWPPs) were obtained from red wine by absorption and elution
from a resin column. Red wine (375 mL/d), white wine (375 mL/d), RWPPs (1 g/d, equivalent
to 375 mL redwine/d) in capsules, RWPPs (1 g/d) dissolved in white wine, or a control
alcoholic drink (40 g ethanol/d) was given to groups of 6-9 healthy men for 2 wk. Plasma
LDL was separated by ultracentrifugation and desalted by dialyzing against a phosphate
buffer without EDTA. In the copper-catalyzed peroxidation of LDL (copper-diene assay), the …
from a resin column. Red wine (375 mL/d), white wine (375 mL/d), RWPPs (1 g/d, equivalent
to 375 mL redwine/d) in capsules, RWPPs (1 g/d) dissolved in white wine, or a control
alcoholic drink (40 g ethanol/d) was given to groups of 6-9 healthy men for 2 wk. Plasma
LDL was separated by ultracentrifugation and desalted by dialyzing against a phosphate
buffer without EDTA. In the copper-catalyzed peroxidation of LDL (copper-diene assay), the …
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