Contribution of arginase activation to vascular dysfunction in cigarette smoking
Background Cigarette smoke increases the risk of several cardiovascular diseases and has
synergistic detrimental effects when present with other risks that contribute to its
pathogenesis. Oxidative injury to the endothelium via reactive oxygen species (ROS) and
nitric oxide (NO) dysregulation is a common denominator of smoking-induced alterations in
vascular function. However, the mechanisms underlying ROS and NO dysregulation due to
smoking remain unclear. We tested if arginase (Arg) activation/upregulation contributes to …
synergistic detrimental effects when present with other risks that contribute to its
pathogenesis. Oxidative injury to the endothelium via reactive oxygen species (ROS) and
nitric oxide (NO) dysregulation is a common denominator of smoking-induced alterations in
vascular function. However, the mechanisms underlying ROS and NO dysregulation due to
smoking remain unclear. We tested if arginase (Arg) activation/upregulation contributes to …
以上显示的是最相近的搜索结果。 查看全部搜索结果