Convalescent plasma therapy for COVID-19: a graphical mosaic of the worldwide evidence
SA Klassen, JW Senefeld, KA Senese… - Frontiers in …, 2021 - frontiersin.org
Convalescent plasma has been used worldwide to treat patients hospitalized with
coronavirus disease 2019 (COVID-19) and prevent disease progression. Despite global
usage, uncertainty remains regarding plasma efficacy, as randomized controlled trials
(RCTs) have provided divergent evidence regarding the survival benefit of convalescent
plasma. Here, we argue that during a global health emergency, the mosaic of evidence
originating from multiple levels of the epistemic hierarchy should inform contemporary policy …
coronavirus disease 2019 (COVID-19) and prevent disease progression. Despite global
usage, uncertainty remains regarding plasma efficacy, as randomized controlled trials
(RCTs) have provided divergent evidence regarding the survival benefit of convalescent
plasma. Here, we argue that during a global health emergency, the mosaic of evidence
originating from multiple levels of the epistemic hierarchy should inform contemporary policy …
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