Copper (II) and Nickel (II) complexes of the non-steroidal anti-inflammatory drug indomethacin containing aromatic chelating N, N-donor ligand: Synthesis and …
GG Nnabuike, S Salunke-Gawali, AS Patil… - Journal of Molecular …, 2021 - Elsevier
Abstract Two complexes [Cu (indo) 2 (phen)(H 2 O)]; Cu-1 and [Ni (indo) 2 (phen)(H 2 O) 2].
1.5 H 2 O; Ni-1, were synthesized by the reaction of their respective metal (II) acetates with
indomethacin (indo)[1-(4-chlorobenzoyl)-5‑methoxy‑2-methyl-1H-indole-3-acetic acid)] and
a nitrogen donor heterocyclic ligand 1, 10-phenanthroline (phen) in acetonitrile: water
mixture (9: 1 v/v), by refluxing at 80° C for 3 h. The complexes were characterized by
physicochemical, spectroscopic, and TG analysis. X-ray structural analysis showed that both …
1.5 H 2 O; Ni-1, were synthesized by the reaction of their respective metal (II) acetates with
indomethacin (indo)[1-(4-chlorobenzoyl)-5‑methoxy‑2-methyl-1H-indole-3-acetic acid)] and
a nitrogen donor heterocyclic ligand 1, 10-phenanthroline (phen) in acetonitrile: water
mixture (9: 1 v/v), by refluxing at 80° C for 3 h. The complexes were characterized by
physicochemical, spectroscopic, and TG analysis. X-ray structural analysis showed that both …
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