Copper-catalyzed alkylarylation of activated alkenes using isocyanides as the alkyl source: an efficient radical access to 3, 3-dialkylated oxindoles
Chemical Communications, 2016•pubs.rsc.org
A novel and efficient protocol for the synthesis of 3, 3-dialkylated oxindoles is described. The
method involves a copper-catalyzed tandem radical addition/cyclization of N-
arylacrylamides with the alkyl radicals generated from isocyanides. Two C–C bonds are
formed in a single step.
method involves a copper-catalyzed tandem radical addition/cyclization of N-
arylacrylamides with the alkyl radicals generated from isocyanides. Two C–C bonds are
formed in a single step.
A novel and efficient protocol for the synthesis of 3,3-dialkylated oxindoles is described. The method involves a copper-catalyzed tandem radical addition/cyclization of N-arylacrylamides with the alkyl radicals generated from isocyanides. Two C–C bonds are formed in a single step.
The Royal Society of Chemistry以上显示的是最相近的搜索结果。 查看全部搜索结果