Coronary smooth muscle differentiation from proepicardial cells requires rhoA-mediated actin reorganization and p160 rho-kinase activity

J Lu, TE Landerholm, JS Wei, XR Dong, SP Wu… - Developmental …, 2001 - Elsevier
We recently reported that the first detectable expression of SMC-specific proteins during
coronary smooth muscle cell (CoSMC) differentiation from isolated proepicardial cells was
restricted to cells undergoing epithelial-to-mesenchymal transformation (EMT). The
objectives of this study were to examine more closely the relation between actin cytoskeletal
rearrangements and serum response factor (SRF)-dependent transcription, and to
specifically test whether rhoA–GTPase signaling is required for CoSMC differentiation. We …

[引用][C] Coronary smooth muscle differentiation from proepicardial cells

M Majesky, T Landerholm, J Lu, XR Dong, PT Ku - Atherosclerosis, 2000 - elibrary.ru
Coronary smooth muscle differentiation from proepicardial cellsCORONARY SMOOTH
MUSCLE DIFFERENTIATION FROM PROEPICARDIAL CELLS
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