coronary smooth muscle cell (CoSMC) differentiation from isolated proepicardial cells was
restricted to cells undergoing epithelial-to-mesenchymal transformation (EMT). The
objectives of this study were to examine more closely the relation between actin cytoskeletal
rearrangements and serum response factor (SRF)-dependent transcription, and to
specifically test whether rhoA–GTPase signaling is required for CoSMC differentiation. We …