[HTML][HTML] Cortical phase changes in Alzheimer's disease at 7T MRI: a novel imaging marker
Background Postmortem studies have indicated the potential of high-field magnetic
resonance imaging (MRI) to visualize amyloid depositions in the cerebral cortex. The aim of
this study is to test this hypothesis in patients with Alzheimer's disease (AD). Methods T2*-
weighted MRI was performed in 16 AD patients and 15 control subjects. All magnetic
resonance images were scored qualitatively by visual assessment, and quantitatively by
measuring phase shifts in the cortical gray matter and hippocampus. Statistical analysis was …
resonance imaging (MRI) to visualize amyloid depositions in the cerebral cortex. The aim of
this study is to test this hypothesis in patients with Alzheimer's disease (AD). Methods T2*-
weighted MRI was performed in 16 AD patients and 15 control subjects. All magnetic
resonance images were scored qualitatively by visual assessment, and quantitatively by
measuring phase shifts in the cortical gray matter and hippocampus. Statistical analysis was …
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