Crimp analysis of connective tissue using quantitative second-harmonic generation microscopy

W Lee, H Rahman, ME Kersh, KC Toussaint - Frontiers in Optics, 2017 - opg.optica.org
W Lee, H Rahman, ME Kersh, KC Toussaint
Frontiers in Optics, 2017opg.optica.org
… Abstract: We assess the capacity for second-harmonic generation (SHG) microscopy by
quantitatively characterizing collagen fiber crimp pattern in the posterior cruciate ligament (PCL)
and disclosing the 3D structure in PCL and porcine tendon. OCIS codes: (170.3880)
Medical and biological imaging; (180.4315) Nonlinear … We demonstrated analysis of 3
types of crimps in connective tissue using quantitative SHG microscopy. Using this
approach we suggested a helical fiber model in ligament, which could potentially connect …
Abstract
We assess the capacity for second-harmonic generation (SHG) microscopy by quantitatively characterizing collagen fiber crimp pattern in the posterior cruciate ligament (PCL) and disclosing the 3D structure in PCL and porcine tendon.
opg.optica.org
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