The frequent occurrence of fire disasters in buildings in Nigeria has become a serious threat to the nation’s fragile economy. The impact of this fire accident had created substantial lives, documents and property losses. To ascertain the causes, frequency and giving protection to buildings became challenges to the stakeholders. The aim of this study is to investigate the causes and effects of fire disaster on buildings in Imo State and proffer probable solution that can inhibit fire occurrence or reduce the impact on life and buildings. A set of structured questionnaires was used for data collection which was the primary source. Related literature was reviewed. Data were analysed with basic descriptive statistical tools such as frequency distribution table, percentage, mean, standard deviation with the aid of SPSS version 23.0. 88.1% of the respondents revealed that the use of faulty electrical appliances, use of sub-standard electrical materials and bad workmanship were the major causes of fire incidences in the study area. Again, the result revealed that most of the affected buildings were commercial. From the results obtained the level of fire safety awareness in study area was grossly inadequate because, commercial building operators and government agencies are operating on weak capacity to sufficiently respond to the needs of fire outbreak. The study recommends that there should be public enlightenment, orientation, training and education on fire disaster for commercial building operators so as to know their level of vulnerability to fire hazards and what to do when fire occurs.