Cu (II) salen complex catalyzed synthesis of propargylamines by a three-component coupling reaction

M Tajbaksh, M Farhang, HR Mardani… - Chinese Journal of …, 2013 - Elsevier
M Tajbaksh, M Farhang, HR Mardani, R Hosseinzadeh, Y Sarrafi
Chinese Journal of Catalysis, 2013Elsevier
A one pot three-component coupling reaction of phenylacetylene, aldehyde, and amine
derivatives in the presence of Cu (II) Salen complex as an efficient heterogeneous catalyst
under solvent-free conditions is reported. The catalyst displayed high activity and afforded
the corresponding propargylamines in good to excellent yields. This method provides a wide
range of substrate applicability. The catalyst was reused several times without significant
loss of its catalytic activity.
Abstract
A one pot three-component coupling reaction of phenylacetylene, aldehyde, and amine derivatives in the presence of Cu(II) Salen complex as an efficient heterogeneous catalyst under solvent-free conditions is reported. The catalyst displayed high activity and afforded the corresponding propargylamines in good to excellent yields. This method provides a wide range of substrate applicability. The catalyst was reused several times without significant loss of its catalytic activity.
Elsevier
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