Curcacycline A and B modulate apoptosis induced by heat stress in sheep oocytes during in vitro maturation
IAH Barakat, WKB Khalil, AR Al-Himaidi - Small Ruminant Research, 2016 - Elsevier
The main objective of the current study was to investigate the effect of Curcacycline A and B
against heat stress induced apoptosis. Cumulus-oocyte complexes (COCs) were allocated
in several groups were cultured at 39° C and 42° C in TCM-199 supplemented either with
hormones alone, or with two cyclic peptides isolated from the latex of Jatropha curcas,
namely Curcacycline A and B. In general, the results revealed a concrete reduction in the
maturation rate of sheep oocytes cultured in TCM-199 medium at 42° C. At the same …
against heat stress induced apoptosis. Cumulus-oocyte complexes (COCs) were allocated
in several groups were cultured at 39° C and 42° C in TCM-199 supplemented either with
hormones alone, or with two cyclic peptides isolated from the latex of Jatropha curcas,
namely Curcacycline A and B. In general, the results revealed a concrete reduction in the
maturation rate of sheep oocytes cultured in TCM-199 medium at 42° C. At the same …
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