Current progress in CRISPR‐based diagnostic platforms

K Khambhati, G Bhattacharjee… - Journal of Cellular …, 2019 - Wiley Online Library
Journal of Cellular Biochemistry, 2019Wiley Online Library
The CRISPR‐Cas system is a key technology for genome editing and regulation in a wide
range of organisms and cell types. Recently, CRISPR‐Cas–based diagnostic platform has
shown idealistic properties for pathogen detection. Integrating the CRISPR‐Cas platform
along with lateral flow system allows rapid, sensitive, specific, cheap, and reliable
diagnostic. It has the potential to be in frontline for not only pathogen detection during the
epidemic outbreak, but also cancer, and genetic diseases.
Abstract
The CRISPR‐Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR‐Cas–based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the CRISPR‐Cas platform along with lateral flow system allows rapid, sensitive, specific, cheap, and reliable diagnostic. It has the potential to be in frontline for not only pathogen detection during the epidemic outbreak, but also cancer, and genetic diseases.
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