Introduction: Schizophrenia is a multifactorial psychiatric disease with complex interactions
among the brain and the immune system. A psycho-immune relationship underling
schizophrenia is supported by several studies and integrates a specific area of knowledge-
psychoneuroimmunology. Methods A systematic review was performed by 2009 Preferred
Reporting Items (PRISMA) recommendations. Based on the inclusion/exclusion criteria,
publications with relevant information (evaluated by the Joanna Briggs Institute Critical …

Daniela Rodrigues-Amorim a, Tania Rivera-Baltanás a, Carlos Spuch b, Hector J. Caruncho
c, África González-Fernandez d, Jose M. Olivares a, Roberto C. Agís-Balboa a,⁎ a
Psychiatric Diseases Research Group, Galicia Sur Health Research Institute (IISGS),
Complexo Hospitalario Universitario de Vigo (CHUVI), SERGAS, CIBERSAM, Spain b
Neurology Research Group, Galicia Sur Health Research Institute (IISGS), Complexo
Hospitalario Universitario de Vigo (CHUVI), SERGAS, CIBERSAM, Spain c Division of …