A phytochemical investigation on the chloroform extract of Caesalpinia pulcherrima roots led
to the isolation of ten known furanocassane diterpenoids, vouacapen-5α-ol (1), 8, 9, 11, 14-
didehydrovouacapen-5α-ol (2), 6β-cinnamoyl-7β-hydroxyvouacapen-5α-ol (3), pulcherrin A
(4), pulcherrin B (5), pulcherrin J (6), pulcherrimin A (7), pulcherrimin B (8), pulcherrimin C
(9), and pulcherrimin E (10). Chemical transformation of 3 and 7 gave compounds 6β-
hydroxyisovouacapenol C (11), 6β-cinnamoyl-7β-acetoxyvouacapen-5α-ol (12), and …

Caesalpinia pulcherrima (L.) Sw.(Caesalpiniaceae), commonly called “Pride of Barbados” or
“Paradise Flower”, is an evergreen shrub well distributed in tropical and subtropical regions
of Africa, Asia, Australia, America, and the Caribbean. The plant is a common ornamental
and has been used in traditional medicine as a stimulant, emenagogue, and arbotifacient [1,
2]. In addition, the plant has been found to be useful in the treatment of fever, malaria,
diarrhea, asthma, and skin diseases [3]. A phytochemical investigation of the plant has …