DNA methylation and chromatin: role (s) of methyl-CpG-binding protein ZBTB38
M de Dieuleveult, B Miotto - Epigenetics insights, 2018 - journals.sagepub.com
DNA methylation plays an essential role in the control of gene expression during early
stages of development as well as in disease. Although many transcription factors are
sensitive to this modification of the DNA, we still do not clearly understand how it contributes
to the establishment of proper gene expression patterns. We discuss here the recent
findings regarding the biological and molecular function (s) of the transcription factor
ZBTB38 that binds methylated DNA sequences in vitro and in cells. We speculate how these …
stages of development as well as in disease. Although many transcription factors are
sensitive to this modification of the DNA, we still do not clearly understand how it contributes
to the establishment of proper gene expression patterns. We discuss here the recent
findings regarding the biological and molecular function (s) of the transcription factor
ZBTB38 that binds methylated DNA sequences in vitro and in cells. We speculate how these …
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