DNA-protective effects of sumach (Rhus coriaria L.), a common spice: results of human and animal studies
A Chakraborty, F Ferk, T Simić, A Brantner… - Mutation Research …, 2009 - Elsevier
Sumach (Rhus coriaria L.) is widely used as a spice. The aim of this study was the
investigation of its DNA-protective effects in humans and animals. Prevention of the
formation of strand breaks and oxidized DNA bases as well as the protection against H2O2-
and (±)-anti-benzo [a] pyrene-7, 8-dihydro-diol-9, 10-epoxide (BPDE)-induced DNA-damage
were monitored in human lymphocytes in a placebo controlled trial (N= 8/group) with
ethanolic extract of sumach (3.0 g/day, 3 days) in single cell gel electrophoresis assays …
investigation of its DNA-protective effects in humans and animals. Prevention of the
formation of strand breaks and oxidized DNA bases as well as the protection against H2O2-
and (±)-anti-benzo [a] pyrene-7, 8-dihydro-diol-9, 10-epoxide (BPDE)-induced DNA-damage
were monitored in human lymphocytes in a placebo controlled trial (N= 8/group) with
ethanolic extract of sumach (3.0 g/day, 3 days) in single cell gel electrophoresis assays …
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