Daycare Attendance is Linked to Increased Risk of Respiratory Morbidities in Children Born Preterm with BronchopulmonaryáDysplasia

SA McGrath-Morrow, A Agarwal, S Alexiou… - The Journal of …, 2022 - Elsevier
SA McGrath-Morrow, A Agarwal, S Alexiou, ED Austin, JL Fierro, LP Hayden, K Lai, JC Levin…
The Journal of pediatrics, 2022Elsevier
Objectives To test the hypothesis that daycare attendance among children with
bronchopulmonary dysplasia (BPD) is associated with increased chronic respiratory
symptoms and/or greater health care use for respiratory illnesses during the first 3áyears of
life. Study design Daycare attendance and clinical outcomes were obtained via
standardized instruments for 341 subjects recruited from 9 BPD specialty clinics in the US.
All subjects were former infants born preterm (< 34áweeks) with BPD (71% severe) requiring …
Objectives
To test the hypothesis that daycare attendance among children with bronchopulmonary dysplasia (BPD) is associated with increased chronic respiratory symptoms and/or greater health care use for respiratory illnesses during the first 3áyears of life.
Study design
Daycare attendance and clinical outcomes were obtained via standardized instruments for 341 subjects recruited from 9 BPD specialty clinics in the US. All subjects were former infants born preterm (<34áweeks) with BPD (71% severe) requiring outpatient follow-up between 0 and 3áyears of age. Mixed logistic regression models were used to test for associations.
Results
Children with BPD attending daycare were more likely to have emergency department visits and systemic steroid usage. Children in daycare up to 3áyears of age also were more likely to report trouble breathing, having activity limitations, and using rescue medications when compared with children not in daycare. More severe manifestations were found in children attending daycare between 6 and 12ámonths of chronological age.
Conclusions
In this study, children born preterm with BPD who attend daycare were more likely to visit the emergency department, use systemic steroids, and have chronic respiratory symptoms compared with children not in daycare, indicating that daycare may be a potential modifiable risk factor to minimize respiratory morbidities in children with BPD during the preschool years.
Elsevier
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