[HTML][HTML] Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura
X Feng, P Scheinberg, L Samsel, O Rios, J Chen… - Journal of Thrombosis …, 2012 - Elsevier
Background: We previously found plasma levels of CD40 ligand (CD40L), chemokine (C‐X‐
C motif) ligand 5 (CXCL5), chemokine (C‐C motif) ligand 5 (CCL5) and epidermal growth
factor (EGF) to be low in aplastic anemia (AA) patients and to be correlated with platelet
count. Objectives: To study the association of CD40L, CXCL5, CCL5 and EGF with platelets.
Methods: We measured cytokines in the plasma of immune thrombocytopenic purpura (ITP)
and AA patients using the Luminex assay and confirmed the results in a mouse model and …
C motif) ligand 5 (CXCL5), chemokine (C‐C motif) ligand 5 (CCL5) and epidermal growth
factor (EGF) to be low in aplastic anemia (AA) patients and to be correlated with platelet
count. Objectives: To study the association of CD40L, CXCL5, CCL5 and EGF with platelets.
Methods: We measured cytokines in the plasma of immune thrombocytopenic purpura (ITP)
and AA patients using the Luminex assay and confirmed the results in a mouse model and …
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