Infrared spectroscopy of cells and tissues is prone to Mie scattering distortions, which
grossly obscure the relevant chemical signals. The state‐of‐the‐art Mie extinction extended
multiplicative signal correction (ME‐EMSC) algorithm is a powerful tool for the recovery of
pure absorbance spectra from highly scatter‐distorted spectra. However, the algorithm is
computationally expensive and the correction of large infrared imaging datasets requires
weeks of computations. In this paper, we present a deep convolutional descattering …