Deletion allele of IFNAR1 gene polymorphism (rs17875871) is associated with a lower risk of breast cancer: A preliminary report

S Sarabandi, S Karami, M Heravi, F Tabasi, M Hashemi… - Meta Gene, 2020 - Elsevier
Breast cancer (BC) is one of the most prevalent cancers in females, which causes significant
mortality. The immune system and inflammation are linked to the pathogenesis of BC.
IFNAR1 is an essential part of the immune response in human. To date, no study evaluated
the association between IFNAR1 polymorphism and BC susceptibility. This study was aimed
to investigate the correlation between IFNAR1 gene polymorphism (rs17875871) and
susceptibility to BC, for the first time. This case-control study was done on 192 BC patients …
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