Dematin, a human erythrocyte cytoskeletal protein, is a substrate for a recombinant FIKK kinase from Plasmodium falciparum
GS Brandt, S Bailey - Molecular and biochemical parasitology, 2013 - Elsevier
P. falciparum causes the most deadly form of malaria, resulting from the adherence of
infected red blood cells to blood vessels. During the blood stage of infection, the parasite
secretes a large number of proteins into the host erythrocyte. The secretion of a 20-member
family of protein kinases known as FIKK kinases, after a conserved Phe-Ile-Lys-Lys
sequence motif, is unique to P. falciparum. Identification of physiological substrates of these
kinases may provide perspective on the importance of FIKK kinase activity to P. falciparum …
infected red blood cells to blood vessels. During the blood stage of infection, the parasite
secretes a large number of proteins into the host erythrocyte. The secretion of a 20-member
family of protein kinases known as FIKK kinases, after a conserved Phe-Ile-Lys-Lys
sequence motif, is unique to P. falciparum. Identification of physiological substrates of these
kinases may provide perspective on the importance of FIKK kinase activity to P. falciparum …
以上显示的是最相近的搜索结果。 查看全部搜索结果