Desenvolvimento de metodologia espectrofotométrica multivariada para o controle de qualidade da associação ácido kójico e hidroquinona em dermocosméticos

GN Calaça - 2010 - bdtd.ibict.br
Kojic Acid (KA) and Hydroquinone (HQ) are depigmenting agents used as skinwhitening
cosmetics to treat dyschromias. The need for low cost analytical methodologies that enable
quality control of this association is evident. Due to the characteristics such as high
sensitivity, low cost and operational simplicity, this work aims to use spectrophotometry in
the visible region and multivariate calibration tools, mainly Partial Least Squares Regression
(PLSR) for quantitative etermination of KA and HQ. The method is based on the …
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