Design of a Multi-Epitope Vaccine against Tropheryma whipplei Using Immunoinformatics and Molecular Dynamics Simulation Techniques
TH Albekairi, A Alshammari, M Alharbi, AF Alshammary… - Vaccines, 2022 - mdpi.com
Whipple's disease is caused by T. whipplei, a Gram-positive pathogenic bacterium. It is
considered a persistent infection affecting various organs, more likely to infect males. There
is currently no licensed vaccination available for Whipple's disease; thus, the development
of a chimeric peptide-based vaccine against T. whipplei has the potential to be
tremendously beneficial in preventing Whipple's disease in the future. The present study
aimed to apply modern computational approaches to generate a multi-epitope-based …
considered a persistent infection affecting various organs, more likely to infect males. There
is currently no licensed vaccination available for Whipple's disease; thus, the development
of a chimeric peptide-based vaccine against T. whipplei has the potential to be
tremendously beneficial in preventing Whipple's disease in the future. The present study
aimed to apply modern computational approaches to generate a multi-epitope-based …
[PDF][PDF] Design of a Multi-Epitope Vaccine against Tropheryma whipplei Using Immunoinformatics and Molecular Dynamics Simulation Techniques. Vaccines 2022, 10 …
TH Albekairi, A Alshammari, M Alharbi, AF Alshammary… - 2022 - academia.edu
Whipple's disease is caused by T. whipplei, a Gram-positive pathogenic bacterium. It is
considered a persistent infection affecting various organs, more likely to infect males. There
is currently no licensed vaccination available for Whipple's disease; thus, the development
of a chimeric peptide-based vaccine against T. whipplei has the potential to be
tremendously beneficial in preventing Whipple's disease in the future. The present study
aimed to apply modern computational approaches to generate a multi-epitope-based …
considered a persistent infection affecting various organs, more likely to infect males. There
is currently no licensed vaccination available for Whipple's disease; thus, the development
of a chimeric peptide-based vaccine against T. whipplei has the potential to be
tremendously beneficial in preventing Whipple's disease in the future. The present study
aimed to apply modern computational approaches to generate a multi-epitope-based …
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