… Alzheimer'sdisease (AD) is the leading cause of dementia in the elderly, affecting more than 35 million people worldwide [1]. Aging populations in developed countries ensure that AD …
… ’s early manifestation and instruction for early detection and treatment. Identifying early MCI (… for the early detection of Alzheimer’s disease. A method for early AD detection using …
In a 1981 pupillometric study, we found a supersensitive miotic response to ocular administration of the muscarinic agonist pilo-carpine (0.125%) in patients with Alzhei-mer's dementia …
L Mosconi, M Brys, L Glodzik-Sobanska… - Experimental …, 2007 - Elsevier
… As our ability to detect brain changes related to AD improves, so does our ability to detect patients at increased risk for AD by using neuroimaging. Neuroimaging techniques offer the …
… the promise, possibly in the near future, of disease-modifying therapies have made the characterization of the early stages of Alzheimer'sdisease (AD) a topic of major research interest. …
T Fladby, L Pålhaugen, P Selnes… - … Alzheimer's disease, 2017 - journals.sagepub.com
While APOE ɛ4 is the major genetic risk factor for Alzheimer’s disease (AD), amyloid dysmetabolism is an initial or early event predicting clinical disease and is an important focus for …
SE Counts, MD Ikonomovic, N Mercado, IE Vega… - …, 2017 - Elsevier
The recent failures of potential disease-modifying drugs for Alzheimer'sdisease (AD) may reflect the fact that the enrolled participants in clinical trials are already too advanced to derive …
S Teipel, A Drzezga, MJ Grothe, H Barthel… - The Lancet …, 2015 - thelancet.com
… brain changes related to Alzheimer'sdisease in the research setting are PET-based amyloid markers, which detect molecular pathology specific to Alzheimer'sdisease, and markers of …
W Li, X Lin, X Chen - Neurocomputing, 2020 - Elsevier
… data for early diagnosis of Alzheimer'sdisease (AD) and its … a far better result for AD detection than the methods using … 4D fMRI data is significant for AD detection and can increase the …