Detection of 5-hydroxymethylfurfural and furfural in the aerosol of electronic cigarettes
S Soussy, ELH Ahmad, R Baalbaki… - Tobacco …, 2016 - tobaccocontrol.bmj.com
Tobacco control, 2016•tobaccocontrol.bmj.com
Significance The wide availability of sweet flavours has been hypothesised as a factor in the
popularity of electronic cigarette (ECIG), especially among youth. Saccharides, which are
commonly used to impart a sweet flavour to ECIG liquids, thermally degrade to produce toxic
compounds, like aldehydes and furans. This study investigates the formation of furanic
compounds in aerosols when ECIG liquid solutions of varying sweetener concentrations are
vaped under different power and puff duration. Methods Liquids are prepared by mixing …
popularity of electronic cigarette (ECIG), especially among youth. Saccharides, which are
commonly used to impart a sweet flavour to ECIG liquids, thermally degrade to produce toxic
compounds, like aldehydes and furans. This study investigates the formation of furanic
compounds in aerosols when ECIG liquid solutions of varying sweetener concentrations are
vaped under different power and puff duration. Methods Liquids are prepared by mixing …
Significance
The wide availability of sweet flavours has been hypothesised as a factor in the popularity of electronic cigarette (ECIG), especially among youth. Saccharides, which are commonly used to impart a sweet flavour to ECIG liquids, thermally degrade to produce toxic compounds, like aldehydes and furans. This study investigates the formation of furanic compounds in aerosols when ECIG liquid solutions of varying sweetener concentrations are vaped under different power and puff duration.
Methods
Liquids are prepared by mixing aqueous sucrose, glucose or sorbitol solutions to a 70/30 propylene glycol/glycerin solution. Aerosols are generated and trapped on filter pads using a commercially available ECIG operating at 4.3 and 10.8 W and 4 and 8 s puff duration. Extraction, elimination of matrix interference and quantification are achieved using novel solid phase extraction and gas chromatography tandem mass spectrometry methods (GC-MS).
Results
Well-resolved GC peaks of 5-hydroxymethylfurfural (HMF) and furfural (FA) are detected. Both HMF and FA are quantified in the aerosols of sweet-flavoured e-liquids under various vaping conditions. Levels of furan emissions are significantly correlated with electric power and sweetener concentration and not with puff duration. Unlike saccharides, the formation of HMF and FA from a sugar alcohol is negligible.
Conclusions
The addition of sweeteners to ECIG liquids exposes ECIG user to furans, a toxic class of compounds. Under certain conditions, the per-puff yield of HMF and FA in ECIG emissions is comparable to values reported for combustible cigarettes.
tobaccocontrol.bmj.com
以上显示的是最相近的搜索结果。 查看全部搜索结果