Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients
Background: Tuberculosis (TB) is predominantly an airborne disease. However, quantitative
and qualitative analysis of bio-aerosols containing the aetiological agent, Mycobacterium
tuberculosis (Mtb), has proven very challenging. Our objective is to sample bio-aerosols
from newly diagnosed TB patients for detection and enumeration of Mtb bacilli. Methods: We
monitored each of 35 newly diagnosed, GeneXpert sputum-positive, TB patients during 1
hour confinement in a custom-built Respiratory Aerosol Sampling Chamber (RASC). The …
and qualitative analysis of bio-aerosols containing the aetiological agent, Mycobacterium
tuberculosis (Mtb), has proven very challenging. Our objective is to sample bio-aerosols
from newly diagnosed TB patients for detection and enumeration of Mtb bacilli. Methods: We
monitored each of 35 newly diagnosed, GeneXpert sputum-positive, TB patients during 1
hour confinement in a custom-built Respiratory Aerosol Sampling Chamber (RASC). The …
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