Development and optimization of orally disintegrating tablets containing Centella asiatica solid lipid nanoparticles for supportive therapies of Parkinson's …

H Khotimah, A Aulanni'am… - …, 2022 - f1000research.com
Background: Parkinson's disease (PD) is the most common chronic progressive
neurodegenerative disorder in the older population. In this work, we have developed a
formulation of orally disintegrating tablets (ODTs) containing Centella asiatica (CA)
encapsulated solid lipid nanoparticles (SLNs) with rapid disintegration and dissolution,
thereby providing greater convenience and ease of use to older patients with PD or
dysphagia. Methods: The absorption, distribution, metabolism, excretion, and toxicity …

[PDF][PDF] Development and optimization of orally disintegratin g tablets containing Centella asiatica solid lipid nanoparticle s for supportive therapies of Parkinson's …

OE Puspita, OR Adianingsih, M Mardhiyah, A Setiawan - 2022 - researchgate.net
Background: Parkinson's disease (PD) is the most common chronic progressive
neurodegenerative disorder in the older population. In this work, we have developed a
formulation of orally disintegrating tablets (ODTs) containing Centella asiatica (CA)
encapsulated solid lipid nanoparticles (SLNs) with rapid disintegration and dissolution,
thereby providing greater convenience and ease of use to older patients with PD or
dysphagia. Methods: The absorption, distribution, metabolism, excretion, and toxicity …
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