Drug efflux-transporters serve as a major barrier to anticancer drugs at the target site. One
strategy to enhance the therapeutic efficacy of drugs against cancer is to increase their
available concentrations at the target site by suppressing or modulating efflux-transporters.
This manuscript deals with the development and evaluation of the particle type drug delivery
system made of stearic acid (Solid Lipid Nanoparticle—SLN) and chitosan for the delivery of
Phenethyl Isothiocyanate (PEITC), a tumor-suppressive agent, through the pulmonary route …