systems containing nitrofurazone (NFZ), a topical anti-infective drug, were developed using
freeze–thawing method. Aqueous solutions of nitrofurazone and PVA/SA mixtures in
different weight ratios were mixed homogeneously, placed in petri dishes, freezed at− 20° C
for 18h and thawed at room temperature for 6h, for three consecutive cycles, and evaluated
for swelling ratio, tensile strength, elongation and thermal stability of the hydrogel …