Diclofenac-enriched artificial sediment induces oxidative stress in Hyalella azteca
DGC Oviedo-Gómez, M Galar-Martínez… - Environmental …, 2010 - Elsevier
Diclofenac is a nonsteroidal anti-inflammatory drug widely used in Mexico where it is sold
over the counter. It enters water bodies through municipal and industrial discharges, posing
a risk to water systems and aquatic organisms. Diclofenac-enriched artificial sediment was
used to evaluate the toxicity of this pharmaceutical on the sentinel species Hyalella azteca,
using oxidative stress biomarkers in order to determine if the set of tests used in this study is
a suitable early damage biomarker. The median lethal concentration (72-h LC50) was …
over the counter. It enters water bodies through municipal and industrial discharges, posing
a risk to water systems and aquatic organisms. Diclofenac-enriched artificial sediment was
used to evaluate the toxicity of this pharmaceutical on the sentinel species Hyalella azteca,
using oxidative stress biomarkers in order to determine if the set of tests used in this study is
a suitable early damage biomarker. The median lethal concentration (72-h LC50) was …