[HTML][HTML] Dienogest 2 mg daily in the treatment of adolescents with clinically suspected endometriosis: the VISanne study to assess safety in ADOlescents

AD Ebert, L Dong, M Merz, B Kirsch, M Francuski… - Journal of pediatric and …, 2017 - Elsevier
Abstract Study Objective To study the safety and efficacy of dienogest 2 mg in adolescents
with suspected endometriosis. Design A 52-week, open-label, single-arm study. Setting In
21 study centers, in 6 European countries. Participants Adolescents aged 12 to younger
than 18 years with clinically suspected or laparoscopically confirmed endometriosis.
Interventions Dienogest 2 mg once daily. Main Outcome Measures The primary end point
was relative change in lumbar spine (L2-L4) bone mineral density (BMD) measured using …
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