Differential expression of antimicrobial peptides in active and latent tuberculosis and its relationship with diabetes mellitus
I Gonzalez-Curiel, J Castañeda-Delgado… - Human immunology, 2011 - Elsevier
Tuberculosis (TB) is one of the most important infectious diseases, causing 1.8 million
deaths annually worldwide. This problem has increased because of the association with
human immmunodeficiency virus and diabetes mellitus type 2, mainly in developing
countries. In the past few years it has been highlighted the significance of antimicrobial
peptides in the immunopathogenesis of TB ex vivo and in experimental models studies. In
this study we analyzed the expression of CAMP, DEFA1, DEFB4, and DEFB103A in patients …
deaths annually worldwide. This problem has increased because of the association with
human immmunodeficiency virus and diabetes mellitus type 2, mainly in developing
countries. In the past few years it has been highlighted the significance of antimicrobial
peptides in the immunopathogenesis of TB ex vivo and in experimental models studies. In
this study we analyzed the expression of CAMP, DEFA1, DEFB4, and DEFB103A in patients …