Diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and usual interstitial pneumonia: an unusual “headcheese pattern” with nodules

V Pietrangeli, S Piciucchi, S Tomassetti, C Ravaglia… - Lung, 2015 - Springer
V Pietrangeli, S Piciucchi, S Tomassetti, C Ravaglia, C Gurioli, C Gurioli, A Cavazza…
Lung, 2015Springer
Abstract A 74-year-old non-smoker female presented to our attention with a history of
dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation
associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary
nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed
features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final
diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was …
Abstract
A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.
Springer
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