[HTML][HTML] Diflucortolone valerate loaded solid lipid nanoparticles as a semisolid topical delivery system

FS Abdel-Salam, SA Elkheshen, AA Mahmoud… - Bulletin of faculty of …, 2016 - Elsevier
Solid lipid nanoparticles (SLNs) are promising delivery carriers that have been utilized for
formulation and delivery of various drugs. For topical administration, they are usually
incorporated into gel or cream to increase their residence time, which is time-consuming
process and could affect their stability and characteristics. Preparation of solid lipid
nanoparticles based semisolid formulations could have potential pharmaceutical
applications. The aim of this study was to formulate the corticosteroidal drug, diflucortolone …

Diflucortolone valerate loaded solid lipid nanoparticles as a semisolid topical delivery system

AAM Mahmoud, FS Abdel-Salam, HO Ammar… - Future, 2013 - fue.edu.eg
Solid lipid nanoparticles (SLNs) are promising delivery carriers that have been utilized for
formulation and delivery of various drugs. For topical administration, they are usually
incorporated into gel or cream to increase their residence time, which is time-consuming
process and could affect their stability and characteristics. Preparation of solid lipid
nanoparticles (SLNs)-based semisolid formulations could have potential pharmaceutical
applications. The aim of this study was to formulate the corticosteroidal drug, diflucortolone …
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