Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells
Background Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, isolated
from the traditional Chinese herb Artemisia annua, is recommended as the first-line anti-
malarial drug with low toxicity. DHA has been shown to possess promising anticancer
activities and induce cancer cell death through apoptotic pathways, although the molecular
mechanisms are not well understood. Methods In this study, cell counting kit (CCK-8) assay
was employed to evaluate the survival of DHA-treated ASTC-a-1 cells. The induction of …
from the traditional Chinese herb Artemisia annua, is recommended as the first-line anti-
malarial drug with low toxicity. DHA has been shown to possess promising anticancer
activities and induce cancer cell death through apoptotic pathways, although the molecular
mechanisms are not well understood. Methods In this study, cell counting kit (CCK-8) assay
was employed to evaluate the survival of DHA-treated ASTC-a-1 cells. The induction of …
Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells.
LYY Lu YingYing, CTS Chen TongSheng… - 2009 - cabidigitallibrary.org
Abstract Background: Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin,
isolated from the traditional Chinese herb Artemisia annua, is recommended as the first-line
anti-malarial drug with low toxicity. DHA has been shown to possess promising anticancer
activities and induce cancer cell death through apoptotic pathways, although the molecular
mechanisms are not well understood. Methods: In this study, cell counting kit (CCK-8) assay
was employed to evaluate the survival of DHA-treated ASTC-a-1 cells. The induction of …
isolated from the traditional Chinese herb Artemisia annua, is recommended as the first-line
anti-malarial drug with low toxicity. DHA has been shown to possess promising anticancer
activities and induce cancer cell death through apoptotic pathways, although the molecular
mechanisms are not well understood. Methods: In this study, cell counting kit (CCK-8) assay
was employed to evaluate the survival of DHA-treated ASTC-a-1 cells. The induction of …
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