Direct, indirect, post-infection damages induced by coronavirus in the human body: an overview
Virusdisease, 2022•Springer
Background Severe acute respiratory syndrome Coronavirus-2 invades the cells via ACE2
receptor and damages multiple organs of the human body. Understanding the pathological
manifestation is mandatory to endure the rising post-infection sequel reported in patients
with or without comorbidities. Materials and methods Our descriptive review emphasises the
direct, indirect and post-infection damages due to COVID-19. We have performed an
electronic database search according to the Preferred Reporting Items for Systematic …
receptor and damages multiple organs of the human body. Understanding the pathological
manifestation is mandatory to endure the rising post-infection sequel reported in patients
with or without comorbidities. Materials and methods Our descriptive review emphasises the
direct, indirect and post-infection damages due to COVID-19. We have performed an
electronic database search according to the Preferred Reporting Items for Systematic …
Background
Severe acute respiratory syndrome Coronavirus-2 invades the cells via ACE2 receptor and damages multiple organs of the human body. Understanding the pathological manifestation is mandatory to endure the rising post-infection sequel reported in patients with or without comorbidities.
Materials and methods
Our descriptive review emphasises the direct, indirect and post-infection damages due to COVID-19. We have performed an electronic database search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines with selective inclusion and exclusion criteria.
Results
The included studies substantiated the extensive damages in the multiple organs due to direct and indirect consequences of COVID-19. After an apparent recovery, the prolonged presentation of the symptoms manifests as post-COVID that can be related with persisting viral antigens and dysregulated immune response.
Conclusion
A few of the symptoms of respiratory, cardiovascular, and neuropsychiatric systems that persist or reappear as post-COVID manifestations. Vaccination and preventive programs will effectively reduce the prevalence but, the post-COVID, a multisystem manifestation, will be a significant tribulation to the medical profession. However, the issue can be managed by implementing public health programs, rehabilitation services, and telemedicine virtual supports to raise awareness and reduce panic.
Springer
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