spreading depression (SD), which occurs in a number of pathologies including migraine,
epilepsy, traumatic brain injury (TBI) and brain ischemia requires direct current (DC) coupled
recordings of local field potentials (LFPs). Here, we describe how DC-coupled recordings
can be performed using high-density iridium electrode arrays (silicone probes). We found
that the DC voltage offset of the silicone probe is large and often exceeds the amplifier input …