Directional stimulation of subthalamic nucleus sweet spot predicts clinical efficacy: proof of concept

…, A Nowacki, I Debove, K Petermann, G Tinkhauser… - Brain stimulation, 2019 - Elsevier
… probabilistic sweet spot based on directional stimulation data and individual VTA modelling
can be applied to predict clinically effective directional stimulation and help guide clinicians

Probabilistic subthalamic nucleus stimulation sweet spot integration into a commercial deep brain stimulation programming software can predict effective stimulation …

…, JA Schlaeppi, L Lachenmayer, G Tinkhauser… - … : Technology at the …, 2023 - Elsevier
… that the clinical efficacy of stimulation correlated with higher … Therefore, we used this
directional probabilistic “sweet spot” … our results from retrospective data may be regarded as proof

Stimulation sweet spot in subthalamic deep brain stimulation–myth or reality? A critical review of literature

A de Roquemaurel, T Wirth, N Vijiaratnam… - Stereotactic and …, 2021 - karger.com
… ing an update of the available evidence. Furthermore, ever since … (subthalamic nucleus) and
covered the period between … -quality studies combining directional stimulation with accurate …

Directional deep brain stimulation can target the thalamic “sweet spot” for improving neuropathic dental pain

MT Krüger, JM Avecillas-Chasin… - Operative …, 2021 - journals.lww.com
… This paper describes the technique of using a directional DBS lead to target the “sweet
spot” for the treatment of NDP. DBS of the VPM can ameliorate NDP. Additional combined …

Programming of subthalamic nucleus deep brain stimulation for Parkinson's disease with sweet spot-guided parameter suggestions

S Nordenström, K Petermann, I Debove… - Frontiers in human …, 2022 - frontiersin.org
… Z represent the proportion of correct predictions, the number of … the effect thresholds of a
directional lead. The suggestions were … It was computed with clinical efficiency, ie, input samples …

[HTML][HTML] Sweetspot mapping in deep brain stimulation: strengths and limitations of current approaches

TA Dembek, JC Baldermann… - … : Technology at the …, 2022 - Elsevier
… Deep brain stimulation (DBS) is an established treatment … For example, electric stimulation
of the subthalamic nucleus (… that even if a sweetspot is able to predict clinical outcome, it does …

[HTML][HTML] Connectivity correlates to predict essential tremor deep brain stimulation outcome: evidence for a common treatment pathway

EH Middlebrooks, L Okromelidze, JK Wong… - NeuroImage: Clinical, 2021 - Elsevier
stimulationsweet spots,” as well as assess the value of structural connectivity in predicting
… , MN, USA) or an 8-contact lead or directional lead and pulse generator (Vercise or Vercise …

Sweet spots of standard and directional leads in patients with refractory essential tremor: white matter pathways associated with maximal tremor improvement

JM Avecillas-Chasin, CR Honey, MKS Heran… - Journal of …, 2022 - thejns.org
… According to recent evidence,1 the worsening of tremor is … as well as stimulation to obtain
the best clinical results. … Stimulation of the subthalamic nucleus in a patient with Parkinson …

Analysis of patient-specific stimulation with segmented leads in the subthalamic nucleus

TAK Nguyen, M Djilas, A Nowacki, A Mercanzini… - PLoS …, 2019 - journals.plos.org
… patients may help to predict the best stimulation area. … with directional stimulation through
the small directional electrode … different results, there seems so far no clear evidence in STN …

[HTML][HTML] Electrophysiological sweet spot mapping in deep brain stimulation for Parkinson's disease patients

J Peeters, T Van Bogaert, A Boogers, R Gransier… - Brain Stimulation, 2024 - Elsevier
… Deep brain stimulation (DBS) of the subthalamic nucleus (STN) … separately as well as the
directional levels in ring mode and in … As a general proof-of-concept, our results furthermore …