Discriminative protection against hydroxyl and superoxide anion radicals by quercetin in human leucocytes in vitro

LC Wilms, JCS Kleinjans, EJC Moonen, JJ Briedé - Toxicology in vitro, 2008 - Elsevier
Antioxidants play a vital role in the cellular protection against oxidative damage. Quercetin is
a well-investigated antioxidant and known to be able to protect against cellular oxidative
DNA damage. In this study, we tried to relate the protection by quercetin pre-treatment
against oxidative DNA damage in human leucocytes in vitro to the interaction of quercetin in
solution with hydroxyl and superoxide anion radicals as measured by electron spin
resonance (ESR) spectrometry, using DMPO as a spin trap. Further, scavenging capacity of …

[PDF][PDF] Discriminative protection against hydroxyl and superoxide anion radicals by quercetin in human lymphocytes in vitro

LC Wilms, JCS Kleinjans, EJC Moonen… - … of antioxidative and …, 2007 - academia.edu
Antioxidants play a vital role in the cellular protection against oxidative damage. Quercetin is
a well-investigated antioxidant and known to be able to protect against cellular oxidative
DNA damage. In this study, we tried to relate the protection by quercetin pre-treatment
against oxidative DNA damage in human lymphocytes in vitro to the interaction of quercetin
in solution with hydroxyl and superoxide anion radicals as measured by ESR (Electron Spin
Resonance) spectrometry, using DMPO as a spin trap. Further, scavenging capacity of …
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