Down-regulation of ADRB2 expression is associated with small cell neuroendocrine prostate cancer and adverse clinical outcomes in castration-resistant prostate …
Objectives The net oncogenic effect of β2-adrenergic receptor ADRB2, whose downstream
elements induce neuroendocrine differentiation and whose expression is regulated by
EZH2, is unclear. ADRB2 expression and associated clinical outcomes in metastatic
castration-resistant prostate cancer (mCRPC) are unknown. Methods and materials This
was a retrospective analysis of a multi-center, prospectively enrolled cohort of mCRPC
patients. Metastatic biopsies were obtained at progression, and specimens underwent laser …
elements induce neuroendocrine differentiation and whose expression is regulated by
EZH2, is unclear. ADRB2 expression and associated clinical outcomes in metastatic
castration-resistant prostate cancer (mCRPC) are unknown. Methods and materials This
was a retrospective analysis of a multi-center, prospectively enrolled cohort of mCRPC
patients. Metastatic biopsies were obtained at progression, and specimens underwent laser …
以上显示的是最相近的搜索结果。 查看全部搜索结果