… In South Africa, reports of drug resistance patterns in patients … the pattern of acquired drug
resistance mutations (DRMs) … presence of primary integrase strand-transfer inhibitor (InSTI) …

… identify drug resistance mutations in the protease, reverse transcriptase and integrase regions
… necessarily associate together mutations found in one area of the pol gene product with …

… Secondly, we did not generate in vitro drug susceptibility or replication capacity data on the
strains in this study, so it was not possible to discern whether changes in mutational profiles …

… Our discovery of minor mutations against integrase inhibitors in a country that does not
routinely use them for other than last-step rescue therapy highlights the possibility that …

… In this review, mechanisms of action of licensed RTIs and PIs, and drug resistance will be
described. The mechanisms of IN inhibitors and entry inhibitors are described in detail in other …

… Therefore, we restricted our analysis of ARV-naive sequences to those lacking any of the
93 surveillance drug resistance mutations (SDRMs) that have become established markers of …

… to investigate the mutations in protease (PR), reverse transcriptase (RT), and integrase (IN) …
, which were referred for HIV-1 drug resistance testing during 2017. A nested polymerase …

… used second-generation integrase inhibitors. Moreover, RAL-… reverse transcriptase inhibitors
(NRTIs and NNRTIs, respectively), protease inhibitors (PIs) and fusion inhibitors. The safety …

… drug resistance analysis of all HIV-1 antiretroviral agents (reverse transcriptase, protease
and integrase inhibitors) are increasingly in demand due to introduction of integrase inhibitors …

… classes of anti-HIV drugs: nucleoside reverse transcriptase inhibitors, non-… reverse
transcriptase inhibitors, protease inhibitors, integrase inhibitors, fusion inhibitors, and entry inhibitors. …