Drug-induced immune thrombocytopenia (DITP) can be triggered by a wide range of
medications. Although many cases of DITP are mild, some are characterized by life-
threatening bleeding symptoms. The pathogenesis of DITP is complex, in that at least six
different mechanisms have been proposed by which drug-induced antibodies can promote
platelet destruction. It is possible in many cases to identify antibodies that react with platelets
in the presence of the sensitizing drug, but the required testing is technically demanding and …