DsRNA degradation in the pea aphid (Acyrthosiphon pisum) associated with lack of response in RNAi feeding and injection assay

O Christiaens, L Swevers, G Smagghe - Peptides, 2014 - Elsevier
Over the past decade, RNA interference (RNAi), the sequence-specific suppression of gene
expression, has proven very promising for molecular research in many species, including
model insects as Tribolium castaneum and Apis mellifera. It showed its usefulness to
analyze gene function and its potential to manage pest populations and reduce disease
pathogens. However, in several insects, the efficiency of RNAi is low or very variable at best.
One of the factors that could influence RNAi efficiency in insects is degradation of dsRNA …
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