Study Design. Responses of human mesenchymal stem cells from bone marrow (hBMSCs)
were analyzed under chemical conditions, and then characterization of ion channels was
evaluated by whole-cell patch clamp. Objective. To explore the possibility of differentiation of
human bone marrow-derived mesenchymal stem cells into neuron-like cells in vitro under
different conditions. Summary of Background Data. The generation of mesenchymal stem
cells into neuron-like cells has been studied. However, few of these studies characterized …

Human bone marrow mesenchymal stem cells (hBMSCs) comprise a cell population
capable of self-renewal and multilineage differentiation commonly isolated from bone
marrow aspirates of large bones. Their osteogenic potential has been extensively exploited
for the biological evaluation of scaffolds or biomaterials with applications in bone tissue
engineering. This work aimed to isolate hBMSCs from femoral heads of patients undergoing
total hip arthroplasty and to evaluate their osteogenic potential. Briefly, the trabecular bone …