Early-onset atrial fibrillation and the prevalence of rare variants in cardiomyopathy and arrhythmia genes
ZT Yoneda, KC Anderson, JA Quintana… - JAMA …, 2021 - jamanetwork.com
Importance Early-onset atrial fibrillation (AF) can be the initial manifestation of a more
serious underlying inherited cardiomyopathy or arrhythmia syndrome. Objective To examine
the results of genetic testing for early-onset AF. Design, Setting, and Participants This
prospective, observational cohort study enrolled participants from an academic medical
center who had AF diagnosed before 66 years of age and underwent whole genome
sequencing through the National Heart, Lung, and Blood Institute's Trans-Omics for …
serious underlying inherited cardiomyopathy or arrhythmia syndrome. Objective To examine
the results of genetic testing for early-onset AF. Design, Setting, and Participants This
prospective, observational cohort study enrolled participants from an academic medical
center who had AF diagnosed before 66 years of age and underwent whole genome
sequencing through the National Heart, Lung, and Blood Institute's Trans-Omics for …
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