Effect of KRAS and BRAF mutations on survival of metastatic colorectal cancer after liver resection: a systematic review and meta-analysis
Background The purpose of the study was to evaluate whether the mutational status of
Kirsten rat sarcoma viral oncogene homolog (KRAS) or b-viral oncogene homolog B1
(BRAF) could be an independent prognostic factor in the subset of patients with colorectal
cancer liver metastases (CRLM) who undergo complete liver resection. Materials and
Methods A systematic literature review was performed to identify articles reporting relapse-
free survival (RFS) and/or overall survival (OS) of patients who underwent complete liver …
Kirsten rat sarcoma viral oncogene homolog (KRAS) or b-viral oncogene homolog B1
(BRAF) could be an independent prognostic factor in the subset of patients with colorectal
cancer liver metastases (CRLM) who undergo complete liver resection. Materials and
Methods A systematic literature review was performed to identify articles reporting relapse-
free survival (RFS) and/or overall survival (OS) of patients who underwent complete liver …
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