rats induced by dextran-sulfate sodium (DSS). METHODS: Colitis was induced in male
Sprague-Dawley (SD) rats (170-180 g) by 4% dextran sulfate sodium (DSS, wt/v; MW
54000) in drinking water for 8 d. The treated rats received 4% DSS and SRE orally (100
mg/kg per day). Control rats received either tap water or SRE only. Macroscopic assessment
which included body weight changes, fecal occult blood and stool consistency were …