Effect of artemether-lumefantrine (Coartem) on cytomegalovirus urine viral load during and following treatment for malaria in children
B Barger-Kamate, M Forman, CO Sangare… - Journal of Clinical …, 2016 - Elsevier
Background Artemisinins, commonly used to treat malaria, have shown activity against
cytomegalovirus (CMV) in vitro, in an animal model, and in case reports; however, the in vivo
anti-CMV activity has not been well investigated. Objectives To evaluate whether
artemisinins affect CMV shedding among subjects co-infected with CMV and malaria. Study
design A prospective observational study of children in Mali (6 month–10 year) presenting
with fever. Urine samples were collected at day 0, 3, and 14 from children treated with …
cytomegalovirus (CMV) in vitro, in an animal model, and in case reports; however, the in vivo
anti-CMV activity has not been well investigated. Objectives To evaluate whether
artemisinins affect CMV shedding among subjects co-infected with CMV and malaria. Study
design A prospective observational study of children in Mali (6 month–10 year) presenting
with fever. Urine samples were collected at day 0, 3, and 14 from children treated with …
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