Effect of bevacizumab vs aflibercept on visual acuity among patients with macular edema due to central retinal vein occlusion: the SCORE2 randomized clinical trial
IU Scott, PC VanVeldhuisen, MS Ip, BA Blodi, NL Oden… - Jama, 2017 - jamanetwork.com
Importance Studies have established the efficacy and safety of aflibercept for the treatment
of macular edema due to central retinal vein occlusion. Bevacizumab is used off-label to
treat this condition despite the absence of supporting data. Objective To investigate whether
bevacizumab is noninferior to aflibercept for the treatment of macular edema secondary to
central retinal or hemiretinal vein occlusion. Design, Setting, and Participants The SCORE2
randomized noninferiority clinical trial was conducted at 66 private practice or academic …
of macular edema due to central retinal vein occlusion. Bevacizumab is used off-label to
treat this condition despite the absence of supporting data. Objective To investigate whether
bevacizumab is noninferior to aflibercept for the treatment of macular edema secondary to
central retinal or hemiretinal vein occlusion. Design, Setting, and Participants The SCORE2
randomized noninferiority clinical trial was conducted at 66 private practice or academic …
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