Effect of ginger extract on expression of GATA3, T-bet and ROR-γt in peripheral blood mononuclear cells of patients with Allergic Asthma

M Kardan, A Rafiei, J Ghaffari, R Valadan… - Allergologia et …, 2019 - Elsevier
Introduction and objectives Allergic asthma is a chronic inflammatory disorder of the airways.
Th1, Th2 and Th17 cells are the main cells involved in the pathophysiology of asthma. The
function of these cells is affected by T-bet, GATA3 and RORγt transcription factors
(respectively). Therefore, the aim of this study was to evaluate the effect of ginger (officinal
Roscoe) extract on the expression of T-bet, GATA-3 and ROR-γ in peripheral blood
mononuclear cells (PBMC) of asthmatic patients, in comparison with healthy volunteers as …
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